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DIETHYLISOPROPYLSILYL TRIFLUOROMETHANESULFONATE (CAS NO. 126889-55-2)
Specifications
Highlight:
C8H17F3O3SSi Fluorinated Silane
,Silyl Protection diethylisopropylsilyl trifluoromethanesulfonate
,cas 126889-55-2
Product Name:
Diethylisopropylsilyl Trifluoromethanesulfonate
Appearance:
Clear Liquid
MF:
C8H17F3O3SSi
MW:
278.36
M.P:
No Data Available
B.P:
No Data Available
Density:
No Data Available
Flash point:
No Data Available
Key Attributes
Brand Name:
SISO
Model Number:
126889-55-2
Place of Origin:
China
Payment Terms:
T/T
Product Description
1. High-Precision Silyl Protection Reagent for Complex Organic Synthesis
Diethylisopropylsilyl trifluoromethanesulfonate (DEIPSOTf) is a high-activity, sterically tunable silylation reagent superior to conventional TMS and TBS protecting agents. It features moderate steric hindrance and ultra-high silylation activity, enabling highly selective protection of hydroxyl, amino and carboxyl groups in complex molecular systems under mild and anhydrous conditions. The introduced diethylisopropylsilyl (DEIPS) group exhibits excellent stability towards oxidation, weak alkali and nucleophilic substitution reactions, effectively suppressing side reactions in multi-step synthesis. It can be cleanly removed under mild acidic conditions without damaging the parent molecular skeleton, significantly improving the synthetic yield and structural controllability of fine chemical and pharmaceutical intermediates.
2. High-Efficiency Catalyst & Lewis Acid Activator for Organic Reactions
Possessing strong Lewis acidity and excellent electrophilic activation capability, this silyl triflate can effectively activate carbonyl groups, olefins and hydroxyl active sites, catalyzing a series of classic organic reactions including cyclization, rearrangement, coupling and addition reactions. Compared with conventional metal acid catalysts, it avoids metal residue contamination and harsh reaction conditions. It features high catalytic efficiency, mild reaction conditions and good functional group tolerance, serving as a green and high-efficiency non-metallic catalytic activator for the synthesis of high-purity fine organic compounds and heterocyclic functional derivatives.
3. Precision Molecular Derivatization & Chromatographic Analysis Reagent
This reagent can efficiently perform silylation derivatization on high-polarity substances such as polyols, carbohydrates and amino acids. It replaces active hydrogen in polar groups to convert strongly polar, poorly volatile compounds into stable, low-polarity, easily volatile silylated derivatives, effectively eliminating chromatographic tailing and improving separation resolution and detection accuracy. With moderate steric hindrance and stable derivatization products, it is suitable for qualitative and quantitative analysis of complex biological samples and fine chemical raw materials via GC and GC-MS, providing high-precision technical support for analytical testing and component identification.
4. Customized Precursor for Functional Organosilicon Intermediate Modification
As a high-activity customized silyl functional precursor, it can introduce diethylisopropylsilyl flexible branched structures into polymer and organosilicon systems via precise silylation grafting reaction. The asymmetric alkyl substituted silicon structure effectively optimizes the interfacial compatibility, low-temperature fluidity and structural flexibility of modified materials, overcoming the brittleness and poor low-temperature resistance of traditional fully methylated silicone materials. It is applicable to the structural modification of high-performance silicone oils, flexible silicone resins and organic-inorganic hybrid materials, improving the mechanical flexibility, solvent resistance and long-term service stability of composite systems.
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